Venlafaxine - Effexor
What is it?
Venlafaxine is a serotonin–noradrenaline reuptake inhibitor (SNRI). It increases both serotonin and noradrenaline levels in the brain.
Why is it used?
Venlafaxine may be chosen for complex anxiety disorders, chronic pain with a behavioural component, or when SSRIs are not effective. It is often used as a long-term medication and is most effective when combined with behaviour modification.
How is it used?
Venlafaxine is given once or twice daily. It must be tapered slowly and not stopped suddenly.
How is it given?
It is available as a capsule or compounded liquid.
What are the side effects?
Some pets may experience mild side effects when starting venlafaxine. Possible side effects include reduced appetite, gastrointestinal upset, or mild sedation, particularly during dose changes.
Other rare effects include vomiting, diarrhoea, constipation, panting, irritability, paradoxical increase in anxiety, noise sensitivity, increased drinking due to dry mouth and light sensitivity. Neurological signs such as trembling and shaking may be seen at higher doses.
If any of the above signs occur, please contact your veterinarian as soon as possible.
Can I use this medication with other supplements or medicines?
Venlafaxine can be safely combined with many supplements and other medications, but it should not be combined with certain drugs without veterinary advice. Always discuss any other products your pet is receiving.
Where do I get it?
Venlafaxine is a human medication available from a pharmacy with a prescription.
Off label use
In Australia, there are very few registered for treating behaviour problems - ie medications that are designed specifically for pets. Instead, we tend to use human medicines that have great evidence for treating behaviour problems. This means many of the medications we use are considered ‘off label’. These medications still have excellent evidence for their use, and lots of data about their effects and side effects, however it is essential that you feel well informed about their off label use. Please read all the information thoroughly to ensure you feel well informed about the risks and benefits of using this medication.